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Dr. ⁨Mamatha Bhat⁩

Dr. ⁨Mamatha Bhat⁩MD, PhD

Transplant Hepatologist, Lead Transplant AI initiative

University Health NetworkTorontoORCID 0000-0003-1960-8449
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About

I lead an interdisciplinary research dedicated to developing and deploying multimodal AI tools for personalized, data-driven care of patients along their liver transplant journey.

Areas of focus

Liver TransplantArtificial Intelligence

Experience & education

MD · McGill University

2001 — 2005

PhD · University of Toronto

Medical Biophysics

2013 — 2018

Transplant Hepatology fellowship · Mayo Clinic

2012 — 2013

Hepatologist, Clinician-Scientist · University Health Network

2015 — present

Publications

Intersectionality in AI and Machine Learning for Health Care: Protocol for a Scoping Review.

Dinh, Duy A, St Louis, Julia, Ziegler, Erin, Gongal, Patricia, Bain, Katie L, Orchanian-Cheff, Ani, et al. · JMIR research protocols · 2026PubMed

Clinical trials and evaluation of AI tools in solid organ transplantation: implications for clinical care, regulatory science, and rare diseases.

Hasjim, Bima J, Koivu, Annabel, Sagheb, Mina, Xu, Wei, Lee, Jennifer Y, Sidhu, Aman, et al. · NPJ digital medicine · 2026PubMed

Multi-modal machine learning highlights recipient genetic and clinical factors as primary drivers of post-transplant MASLD: A two-center study.

Ghosh, Soumita, Prayitno, Khairunnadiya, Maleki, Saba, Azhie, Amirhossein, Hodar, Lila Gonzalez, Hasjim, Bima J, et al. · Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society · 2026PubMed

Advancing regenerative medicine with RNA nanotechnology for chronic and end organ diseases.

Bakrania, Anita, Nguyen Lefebvre, Anh-Thu, de Vries, Rienk, Laflamme, Michael A, Jaeckel, Elmar, Hansen He, Housheng, et al. · Communications medicine · 2026PubMed

Understanding the Mechanisms of Human Liver Regeneration via Characterization of Circulating Extracellular Vesicles.

Sun, Yilin, Pasini, Elisa, Nguyen-Lefebvre, Anh Thu, Bhat, Mamatha · BioMed research international · 2026PubMed

Forecasting Waitlist Trajectories for Patients With Metabolic Dysfunction-Associated Steatohepatitis Cirrhosis: A Neural Network Competing Risk Analysis.

Punchhi, Gopika, Sun, Yingji, Tan, Eunice, Hlaing, Naomi Khaing Than, Liu, Chang, Asrani, Sumeet, et al. · Journal of medical Internet research · 2026PubMed

Impact of Diverse Clinical Characteristics on Survival Benefit of Liver Transplantation.

Alim, Mouaid, Lawendy, Bishoy, Chen, Shiyi, Than Hlaing, Naomi Khaing, Maleki, Saba, Bhat, Mamatha · Journal of transplantation · 2026PubMed

Cancer Genomic Alterations and Microenvironmental Features Encode Synergistic Interactions with Disease Outcomes.

Bayati, Masroor, Klein, Zoe P, Bahcheli, Alexander T, Slobodyanyuk, Mykhaylo, To, Jeffrey, Cheng, Kevin C L, et al. · Molecular cancer research : MCR · 2025PubMed

Topoisomerase IIb binding delineates localized mutational processes and driver mutations in cancer genomes.

Uuskula-Reimand, Liis, Lee, Christian A, Oh, Robin H, Klein, Zoe P, Adler, Nina, Akhtar Alvi, Sana, et al. · Nature communications · 2025PubMed

Navigating the "specific etiology" steatohepatitis category: Evaluation and management of nonalcohol/nonmetabolic dysfunction-associated steatohepatitis.

Khan, Mohammad Qasim, Hassan, Sara, Lizaola-Mayo, Blanca C, Bhat, Mamatha, Watt, Kymberly D · Hepatology (Baltimore, Md.) · 2025PubMed

Chronic Hepatitis B Patients Referred for Liver Transplantation After Nucleos(t)ide Analog Cessation.

Hirode, Grishma, Kilany, Mai, Pi, Steven, Kim, Audrey, Bhat, Mamatha, Van Uum, Rafique, et al. · Journal of viral hepatitis · 2025PubMed

Utilization of biomarkers for alcohol use in candidates for liver transplantation with alcohol-associated liver disease.

Lynch, Marie-Josee, Carrique, Lauren, Hendershot, Christian S, Wozniak, Hannah, Kulasingam, Vathany, Le Foll, Bernard, et al. · Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society · 2025PubMed

RNA nanomedicine in liver diseases.

Bakrania, Anita, Mo, Yulin, Zheng, Gang, Bhat, Mamatha · Hepatology (Baltimore, Md.) · 2025PubMed

GraftIQ: Hybrid multi-class neural network integrating clinical insight for multi-outcome prediction in liver transplant recipients.

Sharma, Divya, Gotlieb, Neta, Chahal, Daljeet, Ahn, Joseph C, Engel, Bastian, Taubert, Richard, et al. · Nature communications · 2025PubMed

Utilizing Machine Learning to Predict Liver Allograft Fibrosis by Leveraging Clinical and Imaging Data.

Rabindranath, Madhumitha, Sun, Yingji, Khalili, Korosh, Bhat, Mamatha · Clinical transplantation · 2025PubMed

Artificial intelligence applied to 'omics data in liver disease: towards a personalised approach for diagnosis, prognosis and treatment.

Ghosh, Soumita, Zhao, Xun, Alim, Mouaid, Brudno, Michael, Bhat, Mamatha · Gut · 2025PubMed

Glucagon-like peptide-1 receptor agonists and sodium-glucose cotransporter-2 inhibitors for the treatment of diabetes mellitus in liver transplant recipients.

Zheng, Katina, Azhie, Amirhossein, You, Xiaoting, Naghibzadeh, Maryam, Tan, Eunice, Naimimohasses, Sara, et al. · Diabetes, obesity & metabolism · 2024PubMed

Pursuing living donor liver transplantation improves outcomes of patients with autoimmune liver diseases: An intention-to-treat analysis.

Jones, Owen, Claasen, Marco P A W, Ivanics, Tommy, Choi, Woo Jin, Gavaria, Felipe, Rajendran, Luckshi, et al. · Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society · 2024PubMed

Acyl-CoA Thioesterase 1 Contributes to Transition of Steatosis to Metabolic-Associated Steatohepatitis.

Pasini, Elisa, Baciu, Cristina, Angeli, Marc, Arendt, Bianca, Pellegrina, Diogo, Reimand, Juri, et al. · International journal of hepatology · 2024PubMed

Impact of living donor liver transplantation on long-term cardiometabolic and graft outcomes in cirrhosis due to nonalcoholic steatohepatitis.

Karnam, Ravikiran S, Azhie, Amirhossein, Yang, Cathy, Rogalsky, Andrew, Chen, Shiyi, Xu, Wei, et al. · Clinical transplantation · 2023PubMed

Living donor liver transplantation can address disparities in transplant access for patients with primary sclerosing cholangitis.

Onofrio, Fernanda, Zheng, Katina, Xu, Cherry, Chen, Shiyi, Xu, Wei, Vyas, Mary, et al. · Hepatology communications · 2023PubMed

Predicting the outcome of liver transplantation in patients with non-alcoholic steatohepatitis cirrhosis: The NASH LT risk-benefit calculator.

Karnam, Ravikiran S, Punchhi, Gopika, Mitsakakis, Nicholas, Chen, Shiyi, Saracino, Giovanna, Lilly, Leslie, et al. · Clinical transplantation · 2023PubMed

Achieving tolerance modifies cancer susceptibility profiles in liver transplant recipients.

Bhat, Mamatha, Pasini, Elisa, Patel, Preya, Yu, Jeffrey, Baciu, Cristina, Kurian, Sunil M, et al. · Cancer medicine · 2023PubMed

Biomarkers and predictive models of early allograft dysfunction in liver transplantation - A systematic review of the literature, meta-analysis, and expert panel recommendations.

Liu, Jiang, Martins, Paulo N, Bhat, Mamatha, Pang, Li, Yeung, Oscar W H, Ng, Kevin T P, et al. · Clinical transplantation · 2022PubMed

The promise of artificial intelligence for predictive biomarkers in hepatology.

Bhat, Mamatha, Rabindranath, Madhumitha · Hepatology international · 2022PubMed

Phase II clinical trial of cabozantinib for the treatment of recurrent hepatocellular carcinoma after liver transplantation.

Azhie, Amirhossein, Grant, Robert C, Herman, Michael, Wang, Lisa, Knox, Jennifer J, Bhat, Mamatha · Future oncology (London, England) · 2022PubMed

Feasibility of a Home-Based Exercise Program for Managing Posttransplant Metabolic Syndrome in Lung and Liver Transplant Recipients: Protocol for a Pilot Randomized Controlled Trial.

Rozenberg, Dmitry, Santa Mina, Daniel, Nourouzpour, Sahar, Camacho Perez, Encarna, Stewart, Brooke Lyn, Wickerson, Lisa, et al. · JMIR research protocols · 2022PubMed

Characterization and predictive functional profiles on metagenomic 16S rRNA data of liver transplant recipients: A longitudinal study.

Sivaraj, Saranya, Copeland, Julia K, Malik, Anshu, Pasini, Elisa, Angeli, Marc, Azhie, Amirhossein, et al. · Clinical transplantation · 2022PubMed

Machine Learning Approach to Classify Cardiovascular Disease in Patients With Nonalcoholic Fatty Liver Disease in the UK Biobank Cohort.

Sharma, Divya, Gotlieb, Neta, Farkouh, Michael E, Patel, Keyur, Xu, Wei, Bhat, Mamatha · Journal of the American Heart Association · 2022PubMed

The Impact of Primary Liver Disease and Social Determinants in a Mixed Donor Liver Transplant Program: A Single-Center Analysis.

Leung, Kristel K, Kim, Audrey, Hansen, Bettina E, Lilly, Les, Selzner, Nazia, Patel, Keyur, et al. · Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society · 2021PubMed

Combined proteomic/transcriptomic signature of recurrence post-liver transplantation for hepatocellular carcinoma beyond Milan.

Bhat, Mamatha, Clotet-Freixas, Sergi, Baciu, Cristina, Pasini, Elisa, Hammad, Ahmed, Ivanics, Tommy, et al. · Clinical proteomics · 2021PubMed

Remote Mobile Outpatient Monitoring in Transplant (Reboot) 2.0: Protocol for a Randomized Controlled Trial.

Murray, Kevin R, Foroutan, Farid, Amadio, Jennifer M, Posada, Juan Duero, Kozuszko, Stella, Duhamel, Joseph, et al. · JMIR research protocols · 2021PubMed

Systematic integrative analysis of gene expression identifies HNF4A as the central gene in pathogenesis of non-alcoholic steatohepatitis.

Baciu, Cristina, Pasini, Elisa, Angeli, Marc, Schwenger, Katherine, Afrin, Jenifar, Humar, Atul, et al. · PloS one · 2017PubMed

Insights into Sensing Mechanical Forces to Guide Liver Regeneration.

Ray, Ankit, Bhat, Mamatha · Gastroenterology · 2026PubMed

Budesonide in Liver Transplant Recipients requiring Long-term Corticosteroid in Maintenance Immunosuppression: A Retrospective Case Series.

Al-Ghamdi, Khalid, You, Xiaoting, Rizvi, Sameera, Koivu, Annabel, Chen, Shiyi, Jaeckel, Elmar, et al. · Transplantation proceedings · 2026PubMed

A global consensus on the critical care management of acute-on-chronic liver failure patients: the APASL ACLF Beijing Position Paper.

Chen, Tao, Choudhury, Ashok, Liu, Wei, Zhang, Meng, Wu, Wenhui, Xiang, Huiling, et al. · Hepatology international · 2026PubMed

Artificial intelligence predicts recurrent autoimmune hepatitis after liver transplantation in a multicenter cohort study.

Bhat, Mamatha, Sun, Yingji, Manickavel, Praveen, Maleki, Saba, Ronca, Vincenzo, Hansen, Bettina E, et al. · Hepatology communications · 2026PubMed

Artificial Intelligence and Generative Models in Hepatology: From Large Language Models to Digital Pathology in Liver Disease Diagnosis and Treatment.

Peng, Nana, Wang, Mary Yue, Song, Sherlot Juan, Lai, Jimmy Che-To, Hui, Vicki Wing-Ki, Wong, Vincent Wai-Sun, et al. · Clinical and molecular hepatology · 2026PubMed

Third annual transplant AI symposium: from organ matching to digital twins.

Ramesh, Devina, Manickavel, Praveen, Sidhu, Aman, Kremers, Walter K, Mour, Girish, Huebert, Robert C, et al. · Frontiers in transplantation · 2026PubMed

A donor-recipient ranking model to optimize long-term survival post liver transplant.

Tan, Eunice, Wang, Yingke, Sun, Yingji, He, Xi, Rambhatla, Sirisha, Bhat, Mamatha · Scientific reports · 2026PubMed

Cumulative exposure to tacrolimus is associated with increased risk of malignancy for solid organ transplant recipients.

Acuna, Sergio A, Zhao, Xun, Jones-Carr, Maggie, Smith, Graham, Naylor, Kyla, Hasjim, Bima J, et al. · International journal of cancer · 2026PubMed

A novel auto-fluorescent porphyrin-lipid nanoparticle strategy for CTNNB1 gene silencing in hepatocellular carcinoma.

To, Jeffrey C, Apilan, Alyssa, Pasini, Elisa, Mo, Yulin, Chen, Juan, Bakrania, Anita, et al. · Frontiers in oncology · 2026PubMed

A multiagent large language model-based system to simulate the liver transplant selection committee: a retrospective cohort study.

Hasjim, Bima J, Azarfar, Ghazal, Lee, Frank G, Diwan, Tayyab S, Raju, Shilpa, Gross, Jed Adam, et al. · The Lancet. Digital health · 2026PubMed

One-year functional and neuropsychological outcomes of liver transplant recipients undergoing prolonged mechanical ventilation.

Bhat, Mamatha, Wozniak, Hannah, Dong, Victor, Dragoi, Laura, Misra, Shruti, Rozenberg, Dmitry, et al. · Canadian liver journal · 2026PubMed

Screening and care of patients with graft cirrhosis following liver transplantation.

Zheng, Katina, Arisar, Fakhar Ali Qazi, Chen, Shiyi, Xu, Wei, Lilly, Leslie, Selzner, Markus, et al. · Canadian liver journal · 2026PubMed

Machine Learning-Based Evaluation of Combined EBV and CMV Serostatus as Predictors of Post-Transplant Lymphoproliferative Disorder.

Azarfar, Ghazal, Alotaibi, Muath A M, Sun, Yingji, Husain, Shahid, Sidhu, Aman, Bhat, Mamatha, et al. · Transplant international : official journal of the European Society for Organ Transplantation · 2026PubMed

Mapping distinctive responses to bloodstream infections in transplant recipients could guide precision strategies.

Eichenberger, Emily M, Bhat, Mamatha · American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons · 2026PubMed

2024 transplant AI symposium: key AI models shaping the future of transplant care.

Koivu, Annabel, Azarfar, Ghazal, Maleki, Saba, Sidhu, Aman, Bhat, Mamatha · Frontiers in transplantation · 2025PubMed

Impact of Cystic Fibrosis Transmembrane Conductance Regulator Modulating Therapies on Liver Transplant Outcomes.

Naimimohasses, Sara, Ray, Ankit, Tan, Eunice, Wiggins, Asher, Hasjim, Bima J, Chen, Shiyi, et al. · Gastro hep advances · 2026PubMed

Impact of the 6-mo Wait Policy on Transplantation, Resection, and Ablation Outcomes for Patients With Hepatocellular Carcinoma: A National Cancer Database Analysis.

Hasjim, Bima J, Paukner, Mitchell, Kwong, Allison J, Bhat, Mamatha, Ichii, Hirohito, Redfield, Robert R 3rd, et al. · Transplantation · 2026PubMed

Comparing outcomes of deceased-donor and living-donor liver transplants in patients with PVT.

Li, Zhihao, Jones, Owen, Rajendran, Luckshi, Sierra, Laia Aceituno, Magyar, Christian T J, Jaeckel, Elmar, et al. · Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society · 2026PubMed

Plasma Cell-free DNA Methylomes for Hepatocellular Carcinoma Detection and Monitoring After Liver Resection or Transplantation.

Chen, Kui, Li, Zhihao, Kirsh, Bianca O, Luo, Ping, Pedersen, Stephanie, Bucur, Roxana C, et al. · Annals of surgery · 2025PubMed

Donor-recipient age mismatch and outcomes in liver transplantation: A scientific registry of transplant recipients database analysis.

Hasjim, Bima J, Chen, Shi-Yi, Hlaing, Naomi Kt, Ichii, Hirohito, Redfield, Robert R, Imagawa, David K, et al. · World journal of transplantation · 2025PubMed

Responsible adoption of multimodal artificial intelligence in health care: promises and challenges.

Azarfar, Ghazal, Naimimohasses, Sara, Rambhatla, Sirisha, Komorowski, Matthieu, Ferro, Diana, Lewis, Peter R, et al. · The Lancet. Digital health · 2025PubMed

Social Determinants of Health and Liver Transplant Outcomes in U.S. Indigenous Populations.

Hasjim, Bima J, Patel, Meera, Chen, Shiyi, Ichii, Hirohito, Bhat, Mamatha · The American journal of gastroenterology · 2025PubMed

The evolving role of liver transplantation as enzyme replacement therapy in the era of RNA nanotherapies.

Tan, Eunice, Ahimsadasan, Nilah, Than Hlaing, Naomi Khaing, Low, Janessa, Naimimohasses, Sara, Chen, Shiyi, et al. · American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons · 2025PubMed

Large language models for clinical decision support in gastroenterology and hepatology.

Wiest, Isabella Catharina, Bhat, Mamatha, Clusmann, Jan, Schneider, Carolin V, Jiang, Xiaofeng, Kather, Jakob Nikolas · Nature reviews. Gastroenterology & hepatology · 2025PubMed

The Integration of Multi-omics With Artificial Intelligence in Hepatology: A Comprehensive Review of Personalized Medicine, Biomarker Identification, and Drug Discovery.

Ramesh, Devina, Manickavel, Praveen, Ghosh, Soumita, Bhat, Mamatha · Journal of clinical and experimental hepatology · 2025PubMed

Personalized survival benefit estimation from living donor liver transplantation with a novel machine learning method for confounding adjustment.

Gangadhar, Anirudh, Hasjim, Bima J, Zhao, Xun, Sun, Yingji, Chon, Joseph, Sidhu, Aman, et al. · Journal of hepatology · 2025PubMed

Metabolomics Analysis Uncovers Distinct Profiles of Liver Post-Transplant Patients by Immunosuppression Regimen.

Baciu, Cristina, Hasjim, Bima J, Maleki, Saba, Pasini, Elisa, Patel, Meera Kennedybhai, Shojaee, Maryam, et al. · Metabolites · 2025PubMed

Reducing futile donation after circulatory death procurement with machine learning.

Hasjim, Bima J, Bhat, Mamatha · The Lancet. Digital health · 2025PubMed

Stratifying risk in ACLF-3 patients: The impact of circulatory and respiratory failure on one-year post-transplant outcomes.

Wozniak, Hannah, Zhao, Xun, Chen, Shiyi, Herridge, Margaret S, Bhat, Mamatha · Journal of critical care · 2025PubMed

Living Donor Liver Transplantation for Alcohol-related Liver Disease: An Intention-to-treat Analysis.

Magyar, Christian T J, Jones, Owen, Rajendran, Luckshi, Carrique, Lauren, Lynch, Marie-Josee, Li, Zhihao, et al. · Transplantation · 2025PubMed

Evolutionary dynamics of recurrent hepatocellular carcinoma under divergent immune selection pressures.

Chakravarthy, Ankur, Pasini, Elisa, Zhao, Xun, To, Jeffrey, Shen, Shu Yi Roxana, Fischer, Sandra, et al. · Frontiers in oncology · 2025PubMed

Modelling the liver's regenerative capacity across different clinical conditions.

Nguyen-Lefebvre, Anh Thu, Ghosh, Soumita, Baciu, Cristina, Hasjim, Bima J, Naimimohasses, Sara, Oldani, Graziano, et al. · JHEP reports : innovation in hepatology · 2025PubMed

Response to Daungsupawong and Wiwanitkit's editorial comment on "Using machine learning for personalized prediction of longitudinal COVID-19 vaccine responses in transplant recipients".

Ferreira, Victor H, Bhat, Mamatha · American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons · 2025PubMed

Using machine learning for personalized prediction of longitudinal coronavirus disease 2019 vaccine responses in transplant recipients.

Azarfar, Ghazal, Sun, Yingji, Pasini, Elisa, Sidhu, Aman, Brudno, Michael, Humar, Atul, et al. · American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons · 2025PubMed

Machine Learning Prediction Model of Waitlist Outcomes in Patients with Primary Sclerosing Cholangitis.

Zhao, Xun, Naghibzadeh, Maryam, Sun, Yingji, Rahmani, Arya, Lilly, Leslie, Selzner, Nazia, et al. · Transplantation direct · 2025PubMed

Quo vadis autoimmune hepatitis? - Summary of the 5(th) international autoimmune hepatitis group research workshop 2024.

Engel, Bastian, Assis, David N, Bhat, Mamatha, Clusmann, Jan, Drenth, Joost Ph, Gerussi, Alessio, et al. · JHEP reports : innovation in hepatology · 2025PubMed

Long-Term Survival of Canadian Liver Transplant Recipients Remains Stagnant- A Cohort Study on the Evolution of Cause-Specific Mortality.

Zhao, Xun, Xu, Chaoqun, Bera, Chinmay, Arisar, Fakhar Ali Qazi, Naghibzadeh, Maryam, Azhie, Amirhossein, et al. · Digestive diseases and sciences · 2025PubMed

The emerging role of generative artificial intelligence in transplant medicine.

Deeb, Maya, Gangadhar, Anirudh, Rabindranath, Madhumitha, Rao, Khyathi, Brudno, Michael, Sidhu, Aman, et al. · American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons · 2024PubMed

Hybrid Coronary Artery Revascularization Before Liver Transplantation: A Case Report.

Martinez-Perez, Selene, Davierwala, Piroze, McCluskey, Stuart A, Kalra, Sanjog, Luzzi, Carla, McGilvray, Ian, et al. · Journal of cardiothoracic and vascular anesthesia · 2024PubMed

Proceedings of the 2024 Transplant AI Symposium.

Naimimohasses, Sara, Keshavjee, Shaf, Wang, Bo, Brudno, Mike, Sidhu, Aman, Bhat, Mamatha · Frontiers in transplantation · 2024PubMed

Clinical Deployment of Machine Learning Tools in Transplant Medicine: What Does the Future Hold?

Rabindranath, Madhumitha, Naghibzadeh, Maryam, Zhao, Xun, Holdsworth, Sandra, Brudno, Michael, Sidhu, Aman, et al. · Transplantation · 2024PubMed

Hotspot Immune Exhaustion: Key to Liver Transplant Rejection.

Nguyen-Lefebvre, Anh Thu, Bhat, Mamatha · Gastroenterology · 2024PubMed

Ageing with grace and graft.

Attree, Chloe, Kokorelias, Kristina, Sinha, Samir, Bhat, Mamatha · The lancet. Healthy longevity · 2024PubMed

Deep learning-based pathway-centric approach to characterize recurrent hepatocellular carcinoma after liver transplantation.

To, Jeffrey, Ghosh, Soumita, Zhao, Xun, Pasini, Elisa, Fischer, Sandra, Sapisochin, Gonzalo, et al. · Human genomics · 2024PubMed

What Is Hot and New in Basic and Translational Science in Liver Transplantation in 2023? Report of the Basic and Translational Research Committee of the International Liver Transplantation Society.

Bonaccorsi-Riani, Eliano, Ghinolfi, Davide, Czigany, Zoltan, Dondossola, Daniele, Emamaullee, Juliet, Yuksel, Muhammed, et al. · Transplantation · 2024PubMed

Online resources as a source of information for exercise and physical activity in solid organ transplant recipients.

Da Silva, Tania, Momen, Rozhan, Al Kaabi, Noor, Masrur, Muhib, Holdsworth, Sandra, Prevost, Karina, et al. · Frontiers in sports and active living · 2024PubMed

Harnessing Metabolites as Serum Biomarkers for Liver Graft Pathology Prediction Using Machine Learning.

Baciu, Cristina, Ghosh, Soumita, Naimimohasses, Sara, Rahmani, Arya, Pasini, Elisa, Naghibzadeh, Maryam, et al. · Metabolites · 2024PubMed

Perioperative Cardiovascular Risk Assessment and Management in Liver Transplant Recipients: A Review of the Literature Merging Guidelines and Interventions.

Martinez-Perez, Selene, McCluskey, Stuart A, Davierwala, Piroze M, Kalra, Sanjog, Nguyen, Elsie, Bhat, Mamatha, et al. · Journal of cardiothoracic and vascular anesthesia · 2024PubMed

Outcomes of re-referrals of patients with alcohol-associated liver disease, who were previously declined for liver transplantation.

Cox, Ben, Carrique, Lauren, Di Maira, Tommaso, Sales, Isabel, Don, Caitlin, Gomez-Aldana, Andres, et al. · Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society · 2024PubMed

Trajectories of patients relisted for liver transplantation.

Qazi Arisar, Fakhar Ali, Varghese, Rhea, Chen, Shiyi, Xu, Wei, Selzner, Markus, McGilvray, Ian, et al. · Annals of hepatology · 2024PubMed

Should advanced donor age be a deterrent in the utilization of grafts from donation after cardiac death in deceased donor liver transplantation? The Toronto experience.

Ray, Samrat, Shwaartz, Chaya, Sayed, Blayne Amir, Sapisochin, Gonzalo, Ghanekar, Anand, McGilvray, Ian, et al. · Canadian journal of surgery. Journal canadien de chirurgie · 2023PubMed

A Comprehensive Review of Liver Allograft Fibrosis and Steatosis: From Cause to Diagnosis.

Rabindranath, Madhumitha, Zaya, Rita, Prayitno, Khairunnadiya, Orchanian-Cheff, Ani, Patel, Keyur, Jaeckel, Elmar, et al. · Transplantation direct · 2023PubMed

Availability of living donor optimizes timing of liver transplant in high-risk waitlisted cirrhosis patients.

Arisar, Fakhar Ali Qazi, Chen, Shiyi, Chen, Catherine, Shaikh, Noorulsaba, Karnam, Ravikiran Sindhuvalada, Xu, Wei, et al. · Aging · 2023PubMed

Development of a Radiomics-Based Model to Predict Graft Fibrosis in Liver Transplant Recipients: A Pilot Study.

Qazi Arisar, Fakhar Ali, Salinas-Miranda, Emmanuel, Ale Ali, Hamideh, Lajkosz, Katherine, Chen, Catherine, Azhie, Amirhossein, et al. · Transplant international : official journal of the European Society for Organ Transplantation · 2023PubMed

Genomic Analysis of Hair From Celebrated Composer Provides Insight Into Liver Disease Susceptibility.

Naimimohasses, Sara, Bhat, Mamatha · Gastroenterology · 2023PubMed

Exception points for liver transplantation: A Canadian review.

Congly, Stephen E, Marquez, Vladimir, Bhanji, Rahima A, Bhat, Mamatha, Wong, Philip, Huard, Genevieve, et al. · Canadian liver journal · 2023PubMed

Targeting Wnt-beta-Catenin Signaling Pathway for Hepatocellular Carcinoma Nanomedicine.

Bakrania, Anita, To, Jeffrey, Zheng, Gang, Bhat, Mamatha · Gastro hep advances · 2023PubMed

A deep learning framework for personalised dynamic diagnosis of graft fibrosis after liver transplantation: a retrospective, single Canadian centre, longitudinal study.

Azhie, Amirhossein, Sharma, Divya, Sheth, Priya, Qazi-Arisar, Fakhar Ali, Zaya, Rita, Naghibzadeh, Maryam, et al. · The Lancet. Digital health · 2023PubMed

Artificial intelligence, machine learning, and deep learning in liver transplantation.

Bhat, Mamatha, Rabindranath, Madhumitha, Chara, Beatriz Sordi, Simonetto, Douglas A · Journal of hepatology · 2023PubMed

Transcriptomic changes in liver transplant recipients with non-alcoholic steatohepatitis indicate dysregulation of wound healing.

Pellegrina, Diogo, Prayitno, Khairunnadiya, Azhie, Amirhossein, Pasini, Elisa, Baciu, Cristina, Fischer, Sandra, et al. · Frontiers in endocrinology · 2023PubMed

Repurposing UDCA, an FXR Inhibitor, to Prevent SARS-Cov-2 Infection.

Prayitno, Khairunnadiya, Bhat, Mamatha · Gastroenterology · 2023PubMed

Medical Assistance in Dying (MAiD) as a Source of Liver Grafts: Honouring the Ultimate Gift.

Ray, Samrat, Torres-Hernandez, Alejandro, Bleszynski, Michael Sean, Parmentier, Catherine, McGilvray, Ian, Sayed, Blayne Amir, et al. · Annals of surgery · 2023PubMed

What Is Hot and New in Basic and Translational Science in Liver Transplantation in 2022? Report of the Basic and Translational Research Committee of the International Liver Transplantation Society.

Bhat, Mamatha, Dondossola, Daniele, Varghese, Rhea, Czigany, Zoltan, Emamaullee, Juliet, Ghinolfi, Davide, et al. · Transplantation · 2023PubMed

OrganEx: A Promising Solution for Rescuing Organs After Prolonged Ischemia.

Nguyen-Lefebvre, Anh Thu, Bhat, Mamatha · Gastroenterology · 2023PubMed

Artificial intelligence in liver cancers: Decoding the impact of machine learning models in clinical diagnosis of primary liver cancers and liver cancer metastases.

Bakrania, Anita, Joshi, Narottam, Zhao, Xun, Zheng, Gang, Bhat, Mamatha · Pharmacological research · 2023PubMed

Long-term outcomes of retransplantation after live donor liver transplantation: A Western experience.

Ivanics, Tommy, Limkemann, Ashley, Patel, Madhukar S, Claasen, Marco P A W, Rajendran, Luckshi, Choi, Woo JIn, et al. · Surgery · 2023PubMed

Artificial intelligence applied to omics data in liver diseases: Enhancing clinical predictions.

Baciu, Cristina, Xu, Cherry, Alim, Mouaid, Prayitno, Khairunnadiya, Bhat, Mamatha · Frontiers in artificial intelligence · 2022PubMed

Predictors of patient survival following liver transplant in non-alcoholic steatohepatitis: A systematic review and meta-analysis.

Minich, Adam, Arisar, Fakhar Ali Qazi, Shaikh, Noor-Ul Saba, Herman, Leanne, Azhie, Amirhossein, Orchanian-Cheff, Ani, et al. · EClinicalMedicine · 2022PubMed

Divergent trajectories of lean vs obese non-alcoholic steatohepatitis patients from listing to post-transplant: A retrospective cohort study.

Qazi-Arisar, Fakhar Ali, Uchila, Raj, Chen, Catherine, Yang, Cathy, Chen, Shi-Yi, Karnam, Ravikiran Sindhuvalada, et al. · World journal of gastroenterology · 2022PubMed

The promise of machine learning applications in solid organ transplantation.

Gotlieb, Neta, Azhie, Amirhossein, Sharma, Divya, Spann, Ashley, Suo, Nan-Ji, Tran, Jason, et al. · NPJ digital medicine · 2022PubMed

Relationship Between Hepatic Gene Expression, Intestinal Microbiota, and Inferred Functional Metagenomic Analysis in NAFLD.

Pettinelli, Paulina, Arendt, Bianca M, Schwenger, Katherine J P, Sivaraj, Saranya, Bhat, Mamatha, Comelli, Elena M, et al. · Clinical and translational gastroenterology · 2022PubMed

Application of machine learning in liver transplantation: a review.

Tran, Jason, Sharma, Divya, Gotlieb, Neta, Xu, Wei, Bhat, Mamatha · Hepatology international · 2022PubMed

Distinctive clinical and genetic features of lean vs overweight fatty liver disease using the UK Biobank.

Chahal, Daljeet, Sharma, Divya, Keshavarzi, Sareh, Arisar, Fakhar Ali Qazi, Patel, Keyur, Xu, Wei, et al. · Hepatology international · 2022PubMed

Development and validation of an ensemble machine learning framework for detection of all-cause advanced hepatic fibrosis: a retrospective cohort study.

Sarvestany, Soren Sabet, Kwong, Jeffrey C, Azhie, Amirhossein, Dong, Victor, Cerocchi, Orlando, Ali, Ahmed Fuad, et al. · The Lancet. Digital health · 2022PubMed

Predicting Long-term Survival After Liver Transplantation in Patients With NASH Cirrhosis.

Karnam, Ravikiran S, Mitsakakis, Nicholas, Saracino, Giovanna, Lilly, Leslie, Asrani, Sumeet K, Bhat, Mamatha · Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association · 2022PubMed

Hemojuvelin deficiency promotes liver mitochondrial dysfunction and predisposes mice to hepatocellular carcinoma.

Allameh, Abdolamir, Huttmann, Nico, Charlebois, Edouard, Katsarou, Angeliki, Gu, Wen, Gkouvatsos, Konstantinos, et al. · Communications biology · 2022PubMed

What Is Hot and New in Basic and Translational Science in Liver Transplantation in 2020-2021?-Report of the Basic and Translational Research Committee of the International Liver Transplantation Society.

Czigany, Zoltan, Bruggenwirth, Isabel M A, Ekser, Burcin, Abdelrahim, Maen, Bhat, Mamatha, Bonaccorsi-Riani, Eliano, et al. · Transplantation · 2022PubMed

Nanomedicine in Hepatocellular Carcinoma: A New Frontier in Targeted Cancer Treatment.

Bakrania, Anita, Zheng, Gang, Bhat, Mamatha · Pharmaceutics · 2021PubMed

Results of Early Transplantation for Alcohol-Related Cirrhosis: Integrated Addiction Treatment With Low Rate of Relapse.

Carrique, Lauren, Quance, Jill, Tan, Adrienne, Abbey, Susan, Sales, Isabel, Lilly, Les, et al. · Gastroenterology · 2021PubMed

Estrogen Receptor 1 Inhibition of Wnt/beta-Catenin Signaling Contributes to Sex Differences in Hepatocarcinogenesis.

Bhat, Mamatha, Pasini, Elisa, Pastrello, Chiara, Angeli, Marc, Baciu, Cristina, Abovsky, Mark, et al. · Frontiers in oncology · 2021PubMed

Sex Disparity in Liver Transplant and Access to Living Donation.

Karnam, Ravikiran S, Chen, Shiyi, Xu, Wei, Chen, Catherine, Elangainesan, Praniya, Ghanekar, Anand, et al. · JAMA surgery · 2021PubMed

Impact of immunosuppression on incidence of post-transplant diabetes mellitus in solid organ transplant recipients: Systematic review and meta-analysis.

Kotha, Sreelakshmi, Lawendy, Bishoy, Asim, Saira, Gomes, Charlene, Yu, Jeffrey, Orchanian-Cheff, Ani, et al. · World journal of transplantation · 2021PubMed

Clinical Practice Guideline for Solid Organ Donation and Transplantation During the COVID-19 Pandemic.

Weiss, Matthew J, Hornby, Laura, Foroutan, Farid, Belga, Sara, Bernier, Simon, Bhat, Mamatha, et al. · Transplantation direct · 2021PubMed

Metabolic Complications in Liver Transplantation Recipients: How We Can Optimize Long-Term Survival.

Azhie, Amirhossein, Sheth, Priya, Hammad, Ahmed, Woo, Minna, Bhat, Mamatha · Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society · 2021PubMed

Systematic review and meta-analysis of post-transplant diabetes mellitus in liver transplant recipients.

Lawendy, Bishoy, Srinathan, Sujitha, Kotha, Sreelakshmi, Gomes, Charlene, Misra, Shruti, Yu, Jeffrey, et al. · Clinical transplantation · 2021PubMed

Normothermic Ex Situ Liver Perfusion Enhances Mitochondrial Function of DCD Grafts as Evidenced by High-throughput Metabolomics.

Bhat, Mamatha, Linares-Cervantes, Ivan, Pasini, Elisa, Patel, Preya, Goto, Toru, Noguchi, Yuki, et al. · Transplantation · 2021PubMed

Single-Center North American Experience of Liver Transplantation in Autoimmune Hepatitis: Infrequent Indication but Good Outcomes for Patients.

de Quadros Onofrio, Fernanda, Neong, Evon, Adebayo, Danielle, Kollmann, Dagmar, Adeyi, Oyedele Adewale, Fischer, Sandra, et al. · Journal of the Canadian Association of Gastroenterology · 2021PubMed

Long-term mortality risk stratification of liver transplant recipients: real-time application of deep learning algorithms on longitudinal data.

Nitski, Osvald, Azhie, Amirhossein, Qazi-Arisar, Fakhar Ali, Wang, Xueqi, Ma, Shihao, Lilly, Leslie, et al. · The Lancet. Digital health · 2021PubMed

Tacrolimus Impairs Kupffer Cell Capacity to Control Bacteremia: Why Transplant Recipients Are Susceptible to Infection.

Deppermann, Carsten, Peiseler, Moritz, Zindel, Joel, Zbytnuik, Lori, Lee, Woo-Yong, Pasini, Elisa, et al. · Hepatology (Baltimore, Md.) · 2021PubMed

Transcriptomic investigation reveals donor-specific gene signatures in human lung transplants.

Baciu, Cristina, Sage, Andrew, Zamel, Ricardo, Shin, Jason, Bai, Xiao-Hui, Hough, Olivia, et al. · The European respiratory journal · 2021PubMed

Identifying Modifiable Predictors of Long-Term Survival in Liver Transplant Recipients With Diabetes Mellitus Using Machine Learning.

Yasodhara, Angeline, Dong, Victor, Azhie, Amirhossein, Goldenberg, Anna, Bhat, Mamatha · Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society · 2021PubMed

ActiveDriverDB: Interpreting Genetic Variation in Human and Cancer Genomes Using Post-translational Modification Sites and Signaling Networks (2021 Update).

Krassowski, Michal, Pellegrina, Diogo, Mee, Miles W, Fradet-Turcotte, Amelie, Bhat, Mamatha, Reimand, Juri · Frontiers in cell and developmental biology · 2021PubMed

Metabolic Consequences of Solid Organ Transplantation.

Bhat, Mamatha, Usmani, Shirine E, Azhie, Amirhossein, Woo, Minna · Endocrine reviews · 2021PubMed

Liver transplantation in adult polycystic liver disease: the Ontario experience.

Alsager, Mohammed, Neong, Shuet Fong, Gandhi, Radhika, Teriaky, Anouar, Tang, Ephraim, Skaro, Anton, et al. · BMC gastroenterology · 2021PubMed

Integrative analysis of layers of data in hepatocellular carcinoma reveals pathway dependencies.

Bhat, Mamatha, Pasini, Elisa, Pastrello, Chiara, Rahmati, Sara, Angeli, Marc, Kotlyar, Max, et al. · World journal of hepatology · 2021PubMed

Living donor liver paired exchange: A North American first.

Patel, Madhukar S, Mohamed, Zubaida, Ghanekar, Anand, Sapisochin, Gonzalo, McGilvray, Ian, Sayed, Blayne A, et al. · American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons · 2021PubMed

Enteric dysbiosis in liver and kidney transplant recipients: a systematic review.

Sivaraj, Saranya, Chan, Anita, Pasini, Elisa, Chen, Emily, Lawendy, Bishoy, Verna, Elizabeth, et al. · Transplant international : official journal of the European Society for Organ Transplantation · 2020PubMed

Renal Dysfunction After Liver Transplantation: Effect of Donor Type.

Kollmann, Dagmar, Neong, Shuet Fong, Rosales, Roizar, Hansen, Bettina E, Sapisochin, Gonzalo, McCluskey, Stuart, et al. · Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society · 2020PubMed

Lipoprotein-Like Nanoparticle Carrying Small Interfering RNA Against Spalt-Like Transcription Factor 4 Effectively Targets Hepatocellular Carcinoma Cells and Decreases Tumor Burden.

Cruz, William, Huang, Huang, Barber, Brian, Pasini, Elisa, Ding, Lili, Zheng, Gang, et al. · Hepatology communications · 2020PubMed

Applying Machine Learning in Liver Disease and Transplantation: A Comprehensive Review.

Spann, Ashley, Yasodhara, Angeline, Kang, Justin, Watt, Kymberly, Wang, Bo, Goldenberg, Anna, et al. · Hepatology (Baltimore, Md.) · 2020PubMed

Diabetogenic Effects of Immunosuppression: An Integrative Analysis.

Bhat, Mamatha, Pasini, Elisa, Das, Aninditee, Baciu, Cristina, Angeli, Marc, Humar, Atul, et al. · Transplantation · 2020PubMed

Reply.

Galvin, Zita, Patel, Keyur, Bhat, Mamatha · Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society · 2019PubMed

Attitudes of Liver Transplant Candidates Toward Organs From Increased-Risk Donors.

Humar, Sapna S, Liu, Jingqian, Pinzon, Natalia, Kumar, Deepali, Bhat, Mamatha, Lilly, Les, et al. · Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society · 2019PubMed

The basis of liver regeneration: A systems biology approach.

Bhat, Mamatha, Pasini, Elisa, Baciu, Cristina, Angeli, Marc, Humar, Atul, Macparland, Sonya, et al. · Annals of hepatology · 2019PubMed

Live donor liver transplantation for patients with hepatocellular carcinoma offers increased survival vs. deceased donation.

Goldaracena, Nicolas, Gorgen, Andre, Doyle, Adam, Hansen, Bettina E, Tomiyama, Koji, Zhang, Wei, et al. · Journal of hepatology · 2019PubMed

Report of the 24th Annual Congress of the International Liver Transplantation Society.

De Martin, Eleonora, Hessheimer, Amelia, Chadha, Ryan, Kabacam, Gokhan, Rajanayagam, Jeremy, Kirchner, Varvara, et al. · Transplantation · 2019PubMed

Predictors of De Novo Nonalcoholic Fatty Liver Disease After Liver Transplantation and Associated Fibrosis.

Galvin, Zita, Rajakumar, Ramraj, Chen, Emily, Adeyi, Oyedele, Selzner, Markus, Grant, David, et al. · Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society · 2019PubMed

Immunosuppression, Race, and Donor-Related Risk Factors Affect De novo Cancer Incidence Across Solid Organ Transplant Recipients.

Bhat, Mamatha, Mara, Kristin, Dierkhising, Ross, Watt, Kymberly D S · Mayo Clinic proceedings · 2018PubMed

Surgical Complications after Right Hepatectomy for Live Liver Donation: Largest Single-Center Western World Experience.

Gorgen, Andre, Goldaracena, Nicolas, Zhang, Wei, Rosales, Roizar, Ghanekar, Anand, Lilly, Les, et al. · Seminars in liver disease · 2018PubMed

Liver Transplantation for NASH-Related Hepatocellular Carcinoma Versus Non-NASH Etiologies of Hepatocellular Carcinoma.

Sadler, Erin M, Mehta, Neil, Bhat, Mamatha, Ghanekar, Anand, Greig, Paul D, Grant, David R, et al. · Transplantation · 2018PubMed

Epigenetic basis of hepatocellular carcinoma: A network-based integrative meta-analysis.

Bhat, Venkat, Srinathan, Sujitha, Pasini, Elisa, Angeli, Marc, Chen, Emily, Baciu, Cristina, et al. · World journal of hepatology · 2018PubMed

Metformin requires 4E-BPs to induce apoptosis and repress translation of Mcl-1 in hepatocellular carcinoma cells.

Bhat, Mamatha, Yanagiya, Akiko, Graber, Tyson, Razumilava, Nataliya, Bronk, Steve, Zammit, Domenick, et al. · Oncotarget · 2017PubMed

Clinical and virologic outcomes in high-risk adult Epstein-Barr virus mismatched organ transplant recipients.

Kumar, Deepali, Patil, Nikhil, Husain, Shahid, Chaparro, Cecilia, Bhat, Mamatha, Kim, S Joseph, et al. · Clinical transplantation · 2017PubMed

Proposal of a novel MELD exception point system for hepatocellular carcinoma based on tumor characteristics and dynamics.

Bhat, Mamatha, Ghali, Peter, Dupont, Benoit, Hilzenrat, Roy, Tazari, Mahmood, Roy, Andre, et al. · Journal of hepatology · 2017PubMed

Incidence and Predictors of Advanced Liver Fibrosis by a Validated Serum Biomarker in Liver Transplant Recipients.

Bhat, Mamatha, Rollet-Kurhajec, Kathleen C, Bhat, Aparna, Farag, Amanda, Deschenes, Marc, Wong, Philip, et al. · Canadian journal of gastroenterology & hepatology · 2017PubMed

Implication of the intestinal microbiome in complications of cirrhosis.

Bhat, Mamatha, Arendt, Bianca M, Bhat, Venkat, Renner, Eberhard L, Humar, Atul, Allard, Johane P · World journal of hepatology · 2016PubMed

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