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Dr. ⁨Craig Lammert⁩

Dr. ⁨Craig Lammert⁩MD, MCTS

Associate Professor of Medicine & Executive Director, Autoimmune Hepatitis Association | Gastroenterologist & Hepatologist

Indiana University School of MedicineIndianapolis, INORCID 0000-0003-3809-640X
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About

Dr. Craig Lammert is an Associate Professor of Medicine in the Division of Gastroenterology and Hepatology at Indiana University School of Medicine. He is a practicing gastroenterologist and hepatologist at IU Health and Eskenazi Health, with a clinical and research focus on autoimmune liver diseases, including autoimmune hepatitis, primary biliary cholangitis, and primary sclerosing cholangitis. Dr. Lammert is the founder and Executive Director of the Autoimmune Hepatitis Association and leads NIH-funded research into the genetic and environmental risk factors underlying autoimmune hepatitis. He has authored numerous peer-reviewed publications and is an active member of the International Autoimmune Hepatitis Group and AASLD.

Areas of focus

Gastroenterology and HepatologyAutoimmune hepatitisPrimary biliary cholangitisPrimary sclerosing cholangitisDrug-induced liver injuryGenetic and environmental risk factors for liver diseasePatient advocacy and engagement in researchGut microbiota and liver diseaseSocial media and digital cohort research methods

Experience & education

Associate Professor of Medicine · Indiana University School of Medicine

Department of Medicine, Division of GI & Hepatology

2015 — Present

Executive Director & Founder · Autoimmune Hepatitis Association

2015 — Present

Attending, GI/Hepatologist · IU Health

2014 — Present

Attending, GI/Hepatologist · Eskenazi Health

2014 — Present

Instructor of Medicine · Indiana University School of Medicine

Department of Medicine, Division of GI & Hepatology

2015 — 2015

Attending, GI/Hepatologist · Richard Roudebush VAMC

2014 — 2018

GI Fellowship · Mayo Clinic

Rochester, MN

2013

M.C.T.S. · Mayo Clinic

Rochester, MN

2014

Internal Medicine Residency · Emory University

Atlanta, GA

2010

M.D. · Indiana University School of Medicine

2007

M.S. · Indiana University-Purdue University Indianapolis (IUPUI)

2004

B.S. · Purdue University

2002

Publications

Pruritus Is Frequent and Persistent and Impacts Quality of Life Among Patients With Primary Sclerosing Cholangitis.

Dean, Richard, Yazdanfar, Maryam, Zepeda, Joseph, Patel, Isha J, Levy, Cynthia, Lammert, Craig, et al. · Alimentary pharmacology & therapeutics · 2026PubMed

Overlooked Symptoms in Autoimmune Hepatitis Negatively Impact Many Facets of Life.

Jones, Emma, Watkins, Margaret, Anderson, Erin, Gelow, Kayla, Green, Kelsey, Draucker, Claire, et al. · Digestive diseases and sciences · 2023PubMed

Autoimmune hepatitis and metabolic syndrome-associated disease development: a U.S. cohort study.

Jalal, Muhammad I, Brahmbhatt, Mihir, Green, Kelsey, Weinberg, Ethan M, Lammert, Craig, Bittermann, Therese · Alimentary pharmacology & therapeutics · 2022PubMed

Utilization and Impact of Complementary and Alternative Medicines in Symptomatic Autoimmune Hepatitis Patients.

Gelow, Kayla, Chalasani, Sai, Green, Kelsey, Lammert, Craig · Digestive diseases and sciences · 2022PubMed

Patients with Autoimmune Hepatitis Report Lower Lifetime Coffee Consumption.

Lammert, Craig, Chalasani, Sai N, Green, Kelsey, Atkinson, Elizabeth, McCauley, Bryan, Lazaridis, Konstantinos N · Digestive diseases and sciences · 2022PubMed

Effects of immunosuppressive drugs on COVID-19 severity in patients with autoimmune hepatitis.

Efe, Cumali, Lammert, Craig, Tascilar, Koray, Dhanasekaran, Renumathy, Ebik, Berat, Higuera-de la Tijera, Fatima, et al. · Liver international : official journal of the International Association for the Study of the Liver · 2022PubMed

Behaviors, symptoms, and outcomes of North American patients with autoimmune hepatitis during the COVID-19 pandemic.

Vuppalanchi, Vahin, Gelow, Kayla, Green, Kelsey, Vuppalanchi, Raj, Lammert, Craig · Journal of investigative medicine : the official publication of the American Federation for Clinical Research · 2021PubMed

Racial differences in primary sclerosing cholangitis mortality is associated with community socioeconomic status.

Are, Vijay S, Vilar-Gomez, Eduardo, Gromski, Mark A, Akisik, Fatih, Lammert, Craig, Ghabril, Marwan, et al. · Liver international : official journal of the International Association for the Study of the Liver · 2021PubMed

Environmental risk factors are associated with autoimmune hepatitis.

Lammert, Craig, Chalasani, Sai N, Atkinson, Elizabeth J, McCauley, Bryan M, Lazaridis, Konstantinos N · Liver international : official journal of the International Association for the Study of the Liver · 2021PubMed

Outcome of COVID-19 in Patients With Autoimmune Hepatitis: An International Multicenter Study.

Efe, Cumali, Dhanasekaran, Renumathy, Lammert, Craig, Ebik, Berat, Higuera-de la Tijera, Fatima, Aloman, Costica, et al. · Hepatology (Baltimore, Md.) · 2021PubMed

Exploratory Study of Autoantibody Profiling in Drug-Induced Liver Injury with an Autoimmune Phenotype.

Lammert, Craig, Zhu, Chengsong, Lian, Yun, Raman, Indu, Eckert, George, Li, Quan-Zhen, et al. · Hepatology communications · 2020PubMed

Cannabidiol (CBD) Consumption and Perceived Impact on Extrahepatic Symptoms in Patients with Autoimmune Hepatitis.

Mathur, Karan, Vuppalanchi, Vahin, Gelow, Kayla, Vuppalanchi, Raj, Lammert, Craig · Digestive diseases and sciences · 2020PubMed

Black Adult Patients With Acute Liver Failure Are Sicker and More Likely to Undergo Liver Transplantation Than White Patients.

Nephew, Lauren, Zia, Zahra, Ghabril, Marwan, Orman, Eric, Lammert, Craig, Chalasani, Naga · Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society · 2019PubMed

Extrahepatic Autoimmune Diseases are Prevalent in Autoimmune Hepatitis Patients and Their First-Degree Relatives: Survey Study.

Fogel, Rachel, Comerford, Megan, Chilukuri, Prianka, Orman, Eric, Chalasani, Naga, Lammert, Craig · Interactive journal of medical research · 2018PubMed

Leveraging Social Networking Sites for an Autoimmune Hepatitis Genetic Repository: Pilot Study to Evaluate Feasibility.

Comerford, Megan, Fogel, Rachel, Bailey, James Robert, Chilukuri, Prianka, Chalasani, Naga, Lammert, Craig Steven · Journal of medical Internet research · 2018PubMed

Bidirectional Psychosocial Burden in Autoimmune Hepatitis: Mental Health, Caregiver Strain, and the Potential Role of Patient Advocacy Programming.

Gentry, Elizabeth, Montero, Anne Mary, Blessing, Nadia, Apolzan-Smith, Megan, Green, Kelsey, Woods, Mackenzie, et al. · Digestive diseases and sciences · 2026PubMed

Safety and efficacy of zetomipzomib in relapsed or insufficiently responding autoimmune hepatitis: Results from the randomized, double-blind, placebo-controlled, phase 2a PORTOLA study and open-label extension.

Lammert, Craig S, Weinberg, Ethan M, Sclair, Seth N, Fontana, Robert J, Anand, Neel K, Anderl, Janet L, et al. · Hepatology (Baltimore, Md.) · 2026PubMed

Rituximab as Salvage Therapy in Difficult-to-Treat Autoimmune Hepatitis: A Prospective Case Series.

Lammert, Craig, Blessing, Nadia, Arif, Maaz, Minnaganti, Divya, Weber, Regina, Green, Kelsey, et al. · Gastro hep advances · 2026PubMed

Impact of Type 2 Diabetes Mellitus on Liver Fibrosis and Hepatic Steatosis in Patients with Primary Biliary Cholangitis: A Longitudinal Study.

Williams, Elizabeth E, Lammert, Craig, Vuppalanchi, Raj · Digestive diseases and sciences · 2026PubMed

Gaps in Guideline Adherence for Primary Sclerosing Cholangitis in North America-A 5-Year Analysis.

Martins, Adrielly, Reddy, Anish, Dean, Richard, Gordon, Stuart C, Pratt, Daniel, Li, Michael, et al. · Liver international : official journal of the International Association for the Study of the Liver · 2026PubMed

Incidence of Possible Drug-induced Liver Injury Due to Commonly Implicated Agents in the United States.

Lammert, Craig, Teal, Evgenia, Ghabril, Marwan, Chalasani, Naga · Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association · 2025PubMed

Autoimmune Hepatitis and the Pathways and Targets for Therapies.

Wentworth, Brian J, McGrath, Mary, Khanna, Sahil, Lammert, Craig · The American journal of gastroenterology · 2025PubMed

Low socioeconomic status exacerbates unmet health-related needs in patients with autoimmune hepatitis.

Singleton, Carolyn, Carter, Allie, Baker, Brittany, Jones, Emma, Green, Kelsey, Lammert, Craig, et al. · Alimentary pharmacology & therapeutics · 2024PubMed

Distinction of autoimmune hepatitis from drug-induced autoimmune like hepatitis: The answer lies at the interface.

Alkashash, Ahmad, Zhang, Xin, Vuppalanchi, Raj, Lammert, Craig, Saxena, Romil · Journal of hepatology · 2024PubMed

Autoimmune hepatitis: Current and future therapies.

Reau, Nancy S, Lammert, Craig S, Weinberg, Ethan M · Hepatology communications · 2024PubMed

A polygenic risk score for alcohol-associated cirrhosis among heavy drinkers with European ancestry.

Schwantes-An, Tae-Hwi, Whitfield, John B, Aithal, Guruprasad P, Atkinson, Stephen R, Bataller, Ramon, Botwin, Greg, et al. · Hepatology communications · 2024PubMed

Primary Sclerosing Cholangitis Limited to Intrahepatic Bile Ducts Has Distinctly Better Prognosis.

Are, Vijay S, Gromski, Mark A, Akisik, Fatih, Vilar-Gomez, Eduardo, Lammert, Craig, Ghabril, Marwan, et al. · Digestive diseases and sciences · 2024PubMed

Thirty-Day Readmissions Are Largely Not Preventable in Patients With Cirrhosis.

Orman, Eric S, Desai, Archita P, Ghabril, Marwan S, Nephew, Lauren D, Patidar, Kavish R, Holden, John, et al. · The American journal of gastroenterology · 2024PubMed

PROMIS Profile-29 is a valid instrument with distinct advantages over legacy instruments for measuring the quality of life in chronic liver disease.

Desai, Archita P, Madathanapalli, Abhishek, Tang, Qing, Orman, Eric S, Lammert, Craig, Patidar, Kavish R, et al. · Hepatology (Baltimore, Md.) · 2023PubMed

Circulating cell-free messenger RNA secretome characterization of primary sclerosing cholangitis.

Chalasani, Naga, Vuppalanchi, Raj, Lammert, Craig, Gawrieh, Samer, Braun, Jerome V, Zhuang, Jiali, et al. · Hepatology communications · 2023PubMed

Clinical features, outcomes, and HLA risk factors associated with nitrofurantoin-induced liver injury.

Chalasani, Naga, Li, Yi-Ju, Dellinger, Andrew, Navarro, Victor, Bonkovsky, Herbert, Fontana, Robert J, et al. · Journal of hepatology · 2023PubMed

Germline Mutations in CIDEB and Protection against Liver Disease.

Verweij, Niek, Haas, Mary E, Nielsen, Jonas B, Sosina, Olukayode A, Kim, Minhee, Akbari, Parsa, et al. · The New England journal of medicine · 2022PubMed

Large Hepatic Adenomas and Hepatic Adenomatosis: A Multicenter Study of Risk Factors, Interventions, and Complications.

Lammert, Craig, Toal, Emily, Mathur, Karan, Khungar, Vandana, House, Michael, Roberts, Lewis R, et al. · The American journal of gastroenterology · 2022PubMed

Unexplained liver test elevations after SARS-CoV-2 vaccination.

Guardiola, John, Lammert, Craig, Teal, Evgenia, Chalasani, Naga · Journal of hepatology · 2022PubMed

Health-related quality of life is dynamic in alcoholic hepatitis and responds to improvement in liver disease and reduced alcohol consumption.

Madathanapalli, Abhishek, Tang, Qing, Lammert, Craig, Samala, Niharika, Shah, Vijay H, Sanyal, Arun, et al. · Alcoholism, clinical and experimental research · 2022PubMed

HLA-DR Mismatch and Black Race Are Associated With Recurrent Autoimmune Hepatitis After Liver Transplantation.

McCabe, Marshall, Rush, Natalia, Lammert, Craig, Patidar, Kavish R, Nephew, Lauren, Saxena, Romil, et al. · Transplantation direct · 2021PubMed

Short-chain fatty acid and fecal microbiota profiles are linked to fibrosis in primary biliary cholangitis.

Lammert, Craig, Shin, Andrea S, Xu, Huiping, Hemmerich, Christopher, O'Connell, Thomas M, Chalasani, Naga · FEMS microbiology letters · 2021PubMed

Sex disparities in waitlisting and liver transplant for acute liver failure.

Nephew, Lauren D, Zia, Zahra, Ghabril, Marwan, Orman, Eric, Lammert, Craig, Kubal, Chandrashekhar, et al. · JHEP reports : innovation in hepatology · 2021PubMed

An Outbreak Presents An Opportunity to Learn About A Rare Phenotype: Autoimmune Hepatitis After Acute Hepatitis A.

S-Are, Vijay, Yoder, Lindsay, Samala, Niharika, Nephew, Lauren, Lammert, Craig, Vuppalanchi, Raj · Annals of hepatology · 2020PubMed

Hepatic steatosis is highly prevalent but is not correlated with stiffness in autoimmune hepatitis.

Chalasani, Sai, Mathur, Karan, Shammas, Nicole, Orman, Eric, Vuppalanchi, Raj, Lammert, Craig · Medicine · 2020PubMed

Patients With Chronic Liver Disease Suggestive of Nonalcoholic Fatty Liver Disease May Be at Higher Risk for Drug-Induced Liver Injury.

Lammert, Craig, Imler, Timothy, Teal, Evgenia, Chalasani, Naga · Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association · 2019PubMed

Genetic and Environmental Risk Factors for Autoimmune Hepatitis.

Lammert, Craig · Clinical liver disease · 2019PubMed

Novel HLA Class I Alleles Outside the Extended DR3 Haplotype Are Protective against Autoimmune Hepatitis.

Lammert, Craig, McKinnon, Elizabeth J, Chalasani, Naga, Phillips, Elizabeth J · Clinical and translational gastroenterology · 2019PubMed

Older Age and Disease Duration Are Highly Associated with Hepatocellular Carcinoma in Patients with Autoimmune Hepatitis.

Dakhoul, Lara, Jones, Keaton R, Gawrieh, Samer, Ghabril, Marwan, McShane, Chelsey, Vuppalanchi, Raj, et al. · Digestive diseases and sciences · 2019PubMed

A dedicated paracentesis clinic decreases healthcare utilization for serial paracenteses in decompensated cirrhosis.

Cheng, Yao-Wen, Sandrasegaran, Kumar, Cheng, Katherine, Shah, Angela, Ghabril, Marwan, Berry, William, et al. · Abdominal radiology (New York) · 2018PubMed

Digital Cohorts Within the Social Mediome: An Approach to Circumvent Conventional Research Challenges?

Kulanthaivel, Anand, Fogel, Rachel, Jones, Josette, Lammert, Craig · Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association · 2017PubMed

Management of Difficult Cases of Autoimmune Hepatitis.

Lammert, Craig, Loy, Veronica M, Oshima, Kiyoko, Gawrieh, Samer · Current gastroenterology reports · 2016PubMed

Investigation Gone Viral: Application of the Social Mediasphere in Research.

Lammert, Craig, Comerford, Megan, Love, Joshua, Bailey, James Robert · Gastroenterology · 2015PubMed

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