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Dr. ⁨Cosmas Rinaldi A. Lesmana⁩

Dr. ⁨Cosmas Rinaldi A. Lesmana⁩Verified member

ORCID 0000-0001-9992-9968
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About

Cosmas Rinaldi A. Lesmana is an Associate Professor and senior consultant in the Department of Internal Medicine, Hepatobiliary Division, Dr. Cipto Mangunkusumo National General Hospital, Universitas Indonesia in Jakarta. He is also working at Digestive Disease & GI Oncology Centre (DDOC), Medistra Hospital, Jakarta as well as at Department of Gastroenterology & Hepatology Mayapada Hospital Jakarta Selatan, Jakarta as a senior consultant and interventional endoscopist. He has won several awards for his research. One of his types of innovation research with title "Non-Alcoholic Fatty Pancreas Disease (NAFPD) as A Risk Factor for Pancreatic Cancer based on Endoscopic Ultrasound (EUS) Examination: A Single Centre Experience" has been selected for presentation during Digestive Disease Week (DDW) meeting, 2017 in USA. Dr Lesmana is a pioneer of "Endo-Hepatology" in Indonesia as well as in Asia, where he published technique innovation on portal pressure gradient (PPG) measurement through endoscopic ultrasound (EUS) guided only using standard manometer. Another cutting-edge innovation study on endo-hepatology with title "The role of endoscopic ultrasound in portal hypertension management in a tertiary public hospital and its future direction for first-line clinical approach" has also been selected for oral presentation at American Gastroenterological Association (AGA) Scientific Forum, DDW meeting, 2023 in USA. He has been invited for giving live demonstrations on EUS-guided liver biopsy at ENDOCON meeting 2023, Indore, India, EUS-guided PPG measurement at Institute of Liver & Biliary Sciences (ILBS), New Delhi, India during International Liver Cancer Course (ILCC) Meeting 2024 and giving lectures for Post Graduate Course on "Endo-Hepatology" during Brainstorming and Updates on Innovations in Liver Diseases (BUILD) Conference, Mumbai, India, as well as APASL meeting 2024, Kyoto Japan. Dr. Lesmana is a member of several professional associations, including as a Fellow of American College of Physicians (FACP), elected as a Direct Fellow of American College of Gastroenterology (FACG) and a Fellow of Indonesian Association of Internal Medicine (FINASIM). He is a member of Asian Endoscopic Ultrasound (EUS) Group (AEG) and currently, he has been elected as one of Education Sub-Committee member. He has been elected as a member of American Society for Gastrointestinal Endoscopy (ASGE) and member of American Association for Study of Liver Diseases (AASLD). He has published many papers in peer-reviewed international journals.

Areas of focus

HepatologyFatty LiverLiver CirrhosisPortal HypertensionHepatobiliary MalignancyEndoscopyEndo-Hepatology

Publications

Delphi survey to explore core curriculum for training the next generation of hepatologists.

Xu, Xinyi, Shi, Yu, Tacke, Frank, Wai-Sun Wong, Vincent, Li, Wenhao, Sebastiani, Giada, et al. · JHEP reports : innovation in hepatology · 2026PubMed

Letter: Careful Interpretation of Lemborexant Efficacy and Safety in Patients With Cirrhosis. Authors' Reply.

Gani, Rino Alvani, Akbar, Pitt, Hasan, Irsan, Sulaiman, Andri Sanityoso, Lesmana, Cosmas Rinaldi Adithya, Kurniawan, Juferdy, et al. · Alimentary pharmacology & therapeutics · 2026PubMed

The Global ACLF Consensus : the 'Istanbul Document'.

Kulkarni, Anand V, Choudhury, Ashok, Arora, Vinod, Dokmeci, Abdul Kadir, Koshy, Abraham, Gurakar, Ahmet, et al. · Hepatology international · 2026PubMed

Colorectal cancer in metabolic dysfunction-associated steatotic liver disease: an international Delphi consensus statement.

Wu, Chu-Tian, Targher, Giovanni, Byrne, Christopher D, Younossi, Zobair M, Armstrong, Matthew J, Luu, Hung N, et al. · Gut · 2026PubMed

A global consensus on the critical care management of acute-on-chronic liver failure patients: the APASL ACLF Beijing Position Paper.

Chen, Tao, Choudhury, Ashok, Liu, Wei, Zhang, Meng, Wu, Wenhui, Xiang, Huiling, et al. · Hepatology international · 2026PubMed

Clinical Trial: Lemborexant Efficacy and Safety in Liver Cirrhosis-Randomized, Double-Blind, Crossover Clinical Trial.

Gani, Rino Alvani, Akbar, Pitt, Hasan, Irsan, Sulaiman, Andri Sanityoso, Lesmana, Cosmas Rinaldi Adithya, Kurniawan, Juferdy, et al. · Alimentary pharmacology & therapeutics · 2026PubMed

APASL clinical practice guidelines on the management of chronic hepatitis B infection: a 2026 update.

You, Hong, Maiwall, Rakhi, Chen, Jing, Ahn, Sang Hoon, Dokmeci, Kadir, Dou, Xiaoguang, et al. · Hepatology international · 2026PubMed

Case Report: Pancreatic toxoplasmosis: role of endoscopic ultrasound in diagnosis.

Lesmana, Cosmas Rinaldi A, Adiwinata, Randy, Simca, Jennifer, Tanadi, Caroline, Tandarto, Kevin, Marleen, Stella, et al. · Frontiers in gastroenterology (Lausanne, Switzerland) · 2026PubMed

Blood Product Transfusion for Acute Variceal Bleeding in Liver Cirrhosis: Friend or Foe?

Lesmana, Cosmas R Adithya · Journal of clinical and experimental hepatology · 2026PubMed

Endoscopic Innovation Treatment Strategy in Hepatocellular Carcinoma (HCC) Patients Before Immunotherapy: A Case Series Study in Unselected Patients.

Syofyan, Stephen Dario, Kovara, Kenoah, Lesmana, Nicholas Putra, Wiradikarta, Josia Nathanael, Syofyan, Joshua Francisco, Widjaja, Juan Benedict, et al. · JGH open : an open access journal of gastroenterology and hepatology · 2026PubMed

Chronic Hepatitis B Infection: Patient Guidance.

Mak, Lung-Yi, Lai, Jimmy Che-To, Liu, Ken, Lui, Rashid, Chirapongsathorn, Sakkarin, Yew, Kuo Chao, et al. · Journal of gastroenterology and hepatology · 2026PubMed

Impact of Diabetes, Drug-Induced Liver Injury, and Sepsis on Outcomes in Metabolic Dysfunction Associated Fatty Liver Disease-Related Acute-on-Chronic Liver Failure.

Kumar, Ashish, Arora, Anil, Choudhury, Ashok, Arora, Vinod, Rela, Mohamed, Jothimani, Dinesh Kumar, et al. · The American journal of gastroenterology · 2025PubMed

Pan-Asian adapted ESMO Clinical Practice Guidelines for the diagnosis, treatment and follow-up of patients with pancreatic cancer.

Tai, D, Conroy, T, Lee, J J X, Chee, C E, Hao, C-Y, Wijaya, I, et al. · ESMO open · 2025PubMed

Management of acute variceal bleeding: updated APASL guidelines.

Lesmana, Cosmas Rinaldi Adithya, Shukla, Akash, Kumar, Ashish, Shalimar, Qi, Xiaolong, Gani, Rino Alvani, et al. · Hepatology international · 2025PubMed

The Asian Pacific association for the study of the liver clinical practice guidelines for the diagnosis and management of metabolic dysfunction-associated fatty liver disease.

Eslam, Mohammed, Fan, Jian-Gao, Yu, Ming-Lung, Wong, Vincent Wai-Sun, Cua, Ian Homer, Liu, Chun-Jen, et al. · Hepatology international · 2025PubMed

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